ORGANIC CHEMISTRY Chapter 7 7.6C The Stereochemistry of E2 Reactions The Orientation of Groups in the Transition State EtOH S Eto H Br C-C / Br Anti periplanar Syn periplanar transition state transition state (preferred (only with certain rigid molecules) Department of Chemistry, Xiamen UniversityORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 7 7.6C The Stereochemistry of E2 Reactions: The Orientation of Groups in the Transition State C C Br EtO H C C EtO H Br Anti periplanar transition state (preferred) Syn periplanar transition state (only with certain rigid molecules)