Clinical Manifestation Target organ related to accelerated As related to BP level heart angina、MI,SD heart failure Brain IA, brain thrombosis cerebral hemorrhage encephalopath Kidney renal angiopathy renal arteriolosclerosis renal failure Artery blocking lesion aortic dissectionClinical Manifestation Target organ related to accelerated AS related to BP level heart angina、MI，SD heart failure Brain TIA， brain thrombosis cerebral hemorrhage encephalopathy Kidney renal angiopathy renal arteriolosclerosis renal failure Artery blocking lesion aortic dissection