Medical Genetics Women tend to display more prominent mood symptoms and men more negative symptoms. In the first episode of schizophrenia, women are more likely to display intense irritability, anger, and sadness men are more likely to be withdrawn and emotionally apathetic After the first episode these distinctions begin to blur. PMs is not an indication of the onset of schizophrenia in women although the symptoms are strikingly similarMedical Genetics Women tend to display more prominent mood symptoms and men more negative symptoms. In the first episode of schizophrenia, women are more likely to display intense irritability, anger, and sadness; men are more likely to be withdrawn and emotionally apathetic. After the first episode, these distinctions begin to blur. PMS is not an indication of the onset of schizophrenia in women, although the symptoms are strikingly similar