催化抗体催化Ado缩合 感 例:反应式: O Ab 38C2 or Ab 33F12 " ON 4-nitrocinnamaldehyde O2N ab 38 C2: 99%ee (S)-4-Hydroxy-6-(4 nitrophenyl)-5-hexen-2-one Ab33F12:98%ee Hoffmann. G. et al. Am. chem. Soc. 1998.. 2768-2779O2N H O + O Ab 38C2 O2N H OH O (S)-4-Hydroxy-6-(4- nitrophenyl)-5-hexen-2-one 4-nitrocinnamaldehyde or Ab 33F12 Ab 38C2 : 99% ee Ab 33F12：98% ee Hoffmann, G. et al J.Am.Chem.Soc. 1998, 120, 2768-2779 例： 反应式： 催化抗体催化Aldol缩合