B Cell Membrane Proteins Ab production is a multi-step process that generally requires the mutual interaction b/w B cells and T cells Important molecules on the B cell can be categorized as Ag-binding molecules:membrane Ig Distinguished B cells from other lymphocytes and mononuclear cells Signal transduction molecules associated with mIg- transduce signals into the B cell following Ag binding to Ig Iga(CD79a)and IgB(CD79b) Immunoreceptor tyrosine-based activation motif "other"molecules-increase the activatory signal ·CD19,CD21,CD81B Cell Membrane Proteins ◼ Ab production is a multi-step process that generally requires the mutual interaction b/w B cells and T cells ◼ Important molecules on the B cell can be categorized as ◼ Ag-binding molecules: membrane Ig ◼ Distinguished B cells from other lymphocytes and mononuclear cells ◼ Signal transduction molecules associated with mIg – transduce signals into the B cell following Ag binding to Ig ◼ Iga (CD79a) and Igb (CD79b) ◼ Immunoreceptor tyrosine-based activation motif ◼ “other” molecules – increase the activatory signal ◼ CD19, CD21, CD81