124 Chapter 5 glucose ATP Inhibition by I glucose-6-phosphate AD glucose-6-phosphate Stimulated by AMP ATP and ADP ADP fructose-1, 6-biophosphate Stimulated by glucose- ATP by ATP and NADH pyruvate NAD+ buta a strand NADH +H+ NADH haloacetate V nhibited by ATP Isocitrate lated by AMP ADP inhibited by NADH a-oXoglutarate Stimulated by ADP nhibited by NADH Figure 5. 3 Major control points of glycolysis and the TCA cycle. Enzymes: I, hexokinase: Il, phosphofructokinase; Ill, pyruvate kinase; IV, Pyruvate dehydrogenase; V, citrate synthase; VI aconitase; VI, isocitrate dehydrogenase; Vl, a-oXoglutarate dehydrogenas1 24 Chapter 5 Figure 5.3 Major control points of glycolysis and the TCA cycle. Enzymes: I, hexokinase; 11, phosphofructokinase; 111, pyruvate kinase; IV, pyruvate dehydrogenase; V, citrate synthase; VI, aconitase; VII, isocitrate dehydrogenase; VIII, u-oxoglutarate dehydrogenase