MIT Biology Department 7.012: Introductory Biology -Fall 2004 Instructors: Professor Eric Lander, Professor Robert A Weinberg, Dr. Claudette Gardel Name ction 7.012 Problem set 7 Please print out this problem set and record your answers on the printed copy. answers to this problem set are to be turned in at the box outside by 4: 10 wednesday, November 5. Problem sets will not be accepted late Solutions will be posted on the web November 6, 2003 Question 1 A female geneticist has difficulty characterizing flies by their eye color because she herself is red-gree colorblind(an X-linked recessive phenotype ). She has one sister(colorblind) and one brother(not colorblind) a)Sketch a pedigree that includes the geneticist, her sister, her brother, and their parents: indicate genotypes(clearly define your genotype symbols) b)If 8% of males in a human population are red-green colorblind, what are the frequencies of the wild- type and colorblindness alleles? c)What %o of females in this population should be red-green colorblind? d)What of females in this population should be carriers for red-green colorblindness? 7012Fall2003Name:___________________________________ Section:_____ 7.012 Fall 2003 1 7.012 Problem Set 7 Question 1 A female geneticist has difficulty characterizing flies by their eye color because she herself is red-green colorblind (an X-linked recessive phenotype). She has one sister (colorblind) and one brother (not colorblind). a) Sketch a pedigree that includes the geneticist, her sister, her brother, and their parents; indicate genotypes (clearly define your genotype symbols). b) If 8% of males in a human population are red-green colorblind, what are the frequencies of the wild￾type and colorblindness alleles? c) What % of females in this population should be red-green colorblind? d) What % of females in this population should be carriers for red-green colorblindness? Please print out this problem set and record your answers on the printed copy. Answers to this problem set are to be turned in at the box outside by 4:10 Wednesday, November 5. Problem sets will not be accepted late. Solutions will be posted on the web November 6, 2003. MIT Biology Department 7.012: Introductory Biology - Fall 2004 Instructors: Professor Eric Lander, Professor Robert A. Weinberg, Dr. Claudette Gardel