Chromosome is a discrete unit of the genome carrying many genes. Each chromosome counsists of a very long molecule of duplex DNA and an approximately equal mass of proteins. It is visible as a morphological entity only during cell division Chromosome walking describes the sequential isolation of clones carrying overlapping sequences of DNA, allowing large regions of the chromosome to be spanned. Walking is often erformed in order to reach a particular locus of interest cis-acting locus affects the activity only of DNA sequences on its own molecule of DNA; this property usually implies that the locus does not code for protein cis-acting protein has the exceptional property of acting only on the molecule of DNA from which it was expressed cis configuration describes two sites on the same molecule of dna cis/trans test assays the effect of relative configuration on expression of two mutations. In a double heterozygote, two mutations in the same gene show mutant phenotype in trans configuration, wild-type in cis configuration Cistron is the geneti unit defined by the cistrans test; equivalent to gene ib comprising a unit of dn Class ning is a change in the expression of the c region of an immunoglobulin heavy chain during lymphocyte differentiation Clone describes a large number of cells or molecules identical with a single ancestral cell or molecule Cloning vector is a plasmid or phage that is used to ' inserted foreign DNA for the purposes of producing more material or a protein product Closed reading frame contains termination codons that prevent its translation into protein Coated vesicles are vesicles whose membrane has on its surface a layer of the protei clathrin Coconversion is the simultaneous correction of two sites during gene conversion Coding strand of dNa has the same sequence as mRNA Codominant alleles both contribute to the phenotype; neither is dominant over the other Coevolution -see concerted evolution Cognate tRNAs are those recognized by a particular aminoacy-tRNA synthetase Coointegrate structure is produced by fusion of two replicons, one originally possessing a transposon, the other lacking it; the cointegrate has copies of the transposon present at both nctions of the replicons, oriented as directrepeats Cold-sensitive mutant is defective at low temperature but functional at normal temlperature Colony hybridization is a technique for using in situ hy bridization to identify bacteria carrying chimeric vectors whose inserted DNa is homologous with some particular sequence Compatibility group of plasmids contains members unable to coexist in the same bacterial5 chromomeres. Chromosome is a discrete unit of the genome carrying many genes. Each chromosome counsists of a very long molecule of duplex DNA and an approximately equal mass of proteins. It is visible as a morphological entity only during cell division. Chromosome walking describes the sequential isolation of clones carrying overlapping sequences of DNA, allowing large regions of the chromosome to be spanned. Walking is often performed in order to reach a particular locus of interest. cis-acting locus affects the activity only of DNA sequences on its own molecule of DNA; this property usually implies that the locus does not code for protein. cis-acting protein has the exceptional property of acting only on the molecule of DNA from which it was expressed. cis configuration describes two sites on the same molecule of DNA. cis/trans test assays the effect of relative configuration on expression of two mutations. In a double heterozygote, two mutations in the same gene show mutant phenotype in trans configuration, wild-type in cis configuration. Cistron is the geneti unit defined by the cis/trans test; equivalent to gene ib comprising a unit of DNA representing a protein. Class switching is a change in the expression of the c cregion of an immunoglobulin heavy chain during lymphocyte differentiation. Clone describes a large number of cells or molecules identical with a single ancestral cell or molecule. Cloning vector is a plasmid or phage that is used to ‘carry’ inserted foreign DNA for the purposes of producing more material or a protein product. Closed reading frame contains termination codons that prevent its translation into protein. Coated vesicles are vesicles whose membrane has on its surface a layer of the protein clathrin. Coconversion is the simultaneous correction of two sites during gene conversion. Coding strand of DNA has the same sequence as mRNA. Codominant alleles both contribute to the phenotype; neither is dominant over the other. Coevolution —see concerted evolution. Cognate tRNAs are those recognized by a particular aminoacy-tRNA synthetase. Coointegrate structure is produced by fusion of two replicons, one originally possessing a transposon, the other lacking it; the cointegrate has copies of the transposon present at both junctions of the replicons, oriented as directrepeats. Cold-sensitive mutant is defective at low temperature but functional at normal temlperature. Colony hybridization is a technique for using in situ hybridization to identify bacteria carrying chimeric vectors whose inserted DNA is homologous with some particular sequence. Compatibility group of plasmids contains members unable to coexist in the same bacterial