Jaundice at >2 wks of age(persistent) Unconjugated hyperbilirubinemia: Infection, particularly of urinary tract Congenital hypothyroidism: neonatal biochemical screening, clinical manifestations(constipation, dry skin, coarse facies, hypotonia Breast milk jaundice: most common, 15% affected disappears by 3-4 wks of ageJaundice at >2 wks of age(persistent) Unconjugated hyperbilirubinemia: Infection, particularly of urinary tract. Congenital hypothyroidism: neonatal biochemical screening; clinical manifestations (constipation, dry skin, coarse facies, hypotonia) Breast milk jaundice: most common, 15% affected; disappears by 3-4 wks of age