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NLRPI haplotypes tion study of leprosyJ N Engl J Med, 2010, 362(15):1446- associated with leprosy in Brazilian patients[JI. Infect Genet Evol 1447: author reply 1447-1448. DOl: 10. 1056/NEJMe1001451. 2013,19:274279.Dol:10.106/ j- meego.2013 vari- (21 Zhang Q, Fan HW, Zhang JZ, et al. NLRP3 rs35829419 poly- ants in the NOD 2-mediated signaling pathway are associated with morphism is associated with increased susceptibility to multiple susceptibility to Mycobacterium leprae in Indian populations [J] diseases in humans[J]. Genet Mol Res, 2015. 14(4): 13968 PLos One, 2013,8(8): e73103. DOl: 10.1371/journal pone. 13980.DOl:104238/20150 tober.29.17. 0073103 [12] Sales- Marques C, Salomao H, Fava VM, et al. NOD2 and (收稿日期:2017-04-20) CCDC122-LACCI genes are associated with leprosy susceptibility国际流行病学传染病学杂志 !"#$ 年 ! 月第 %& 卷第 ' 期 ()*+, - ./01+2034 ()5+6* 7089 :+;,<=,> !?'$! @34A %&!B3A# ,38>" = 5=204> 8*<1> 0) C=,0D0,0! E3<*F ()10= G-HA - ()5+6* 708! 'IJI! '%"#!$" '&!"'K'A G!H LF=)D :! M0< N! 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