Treatment Resistant to large number of antibiotics ●Prob|ems: Production of B-lactamase Aminoglycosides ineffective in acidic environment of abscess Successful treatment Combination of B-lactum antibiotic and aminoglycoside BIOL 533 17 Lecture 13BIOL 533 17 Lecture 13 Treatment • Resistant to large number of antibiotics • Problems: – Production of -lactamase – Aminoglycosides ineffective in acidic environment of abscess • Successful treatment – Combination of -lactum antibiotic and amioglycoside