1. 4 Milestones NMR 1946-the first spectra of solid compounds 1957-the first spectra of a protein -Rnase a 1982 -the first protein spectra was assigned 1985-the first solution structure of a protein 1997-924 NMR structures in Pdb Today -over 2, 378 structures in PDB X-ray 1913-the first diffraction patterns of crystals were reported 1934-the first protein crystallized and examined-pepsin 1960-the first protein crystal structures- myoglobin, hemoglobin 1997-5012 crystals structures in PDB Today-over 12, 780 structures in PDB THNMR Ref: WagnerG. Nature Structural Biology. 4: 841-844 (1997) AN PBD ANNUAL REPORT 20011.4 Milestones NMR 1946 - the first spectra of solid compounds 1957 - the first spectra of a protein - RNase A 1982 - the first protein spectra was assigned 1985 - the first solution structure of a protein 1997 - 924 NMR structures in PDB Today - over 2,378 structures in PDB X-ray 1913 - the first diffraction patterns of crystals were reported 1934 - the first protein crystallized and examined - pepsin 1960 - the first protein crystal structures - myoglobin, hemoglobin 1997 - 5012 crystals structures in PDB Today - over 12,780 structures in PDB Ref: Wagner G. Nature Structural Biology. 4: 841-844 (1997) PBD ANNUAL REPORT, 2001 THNMR YAN