Differentiation Main manifestations: The main characteristics of flaccidity syndrome are looseness and atrophy of the muscles along with weakness of the limbs or paralysis.These symptoms can not be treated in a short time,so it pertains to a chronic disease and very difficult to cure. Differentiation ◼ Main manifestations: The main characteristics of flaccidity syndrome are looseness and atrophy of the muscles along with weakness of the limbs or paralysis.These symptoms can not be treated in a short time,so it pertains to a chronic disease and very difficult to cure