上商充通大￥ Mechanism of aciclovir Shanghai Jiao Tong University aciclovir viral thymidine kinase acyclo-guanosine monophosphate (acyclo-GMP) ↓cell kinase acyclo-GTP ↓viral DNA polymerase incorporated into viral DNA ↓ chain terminationShanghai Jiao Tong University Mechanism of aciclovir aciclovir ↓viral thymidine kinase acyclo-guanosine monophosphate (acyclo-GMP) ↓cell kinase acyclo-GTP ↓ viral DNA polymerase incorporated into viral DNA ↓ chain termination