Establishing Maximum Residue Limits for Pesticides (continued ■eII An acute reference dose is established if there is a potential acute toxic endpoint for the pesticide,based on a single or daily commodity serving Manufacturers submit to JMPR residue field trials to determine the residue levels based on Good Agricultural Practices (GAPs).The number of trials is based on USDA climate and soil conditions.Establishing Maximum Residue Limits for Pesticides Limits for Pesticides Pesticides (continued) (continued) ƒ An acute reference dose is established if there is a potential acute i d i f h toxic en dpoint for t h e pesticide, based on a single or dail y yg commodit y servin g. ƒ Manufacturers submit to JMPR residue field trials to determine the residue levels based on Good Agricultural Practices (GAPs). The numb f t i l i b d ber of t rials i s based on climate and soil conditions