CNS lesions with mass effect Venous volume Arterial volume Clinical manifestations CSF Brain Mass can present with headache, nausea vomiting, contusion, and lethargy, papilledema, all of which may reflect evidence of increased intracranial pressure Can cause neurologic focal impairment such as vision osS,weakness,sensory loss, aphasia, etc. Norma Compensated Decompensated normal Icp increased ICpCNS lesions with mass effect • Clinical Manifesta2ons • can present with headache, nausea, vomiFng, confusion, and lethargy, papilledema, all of which may reflect evidence of increased intracranial pressure. • Can cause neurologic focal impairment, such as vision loss, weakness, sensory loss, aphasia, etc