house of a relative who is hosting a family reunion.She is hospitalized for ery to replae a broken hip.She is then moved to a nursing e.but she is to ambulate until about a month later.She gets up to bathe e with assistance and she experiences the sudden onset of severe dyspnea (shortness of breath)and goes into cardiac arrest,from which she cannot be resuscitated. Which of the following is most likely to be the immediate cause of death found at autopsy?() A.Acute bron h pneumonia B.Acute renal failr C.Complications of alcohol abuse D.Congestive heart failure E.Pulmonary embolism 58.A 40-year-old man has a history of intravenous sdrug use. Physical examination shows needle tracks in his left antecubital fossa.He has mild scleral icterus (yellow eyeballs).Serologic studies for hepatitis HBsAg and antibodies to hepatitis HCV are positive.He develops hepatocellular carcinoma 15 years later at age 55.Which of the following best explains why this patient veloped h epato ma? Integration of these viruses in the vicinity of protooncogenes B.The ability of these viruses to capture protooncogenes from the host DNA. C.These viruses cause immunosuppression. D.Viral genes inactivate RB and p53 expression E.Virus injury to liver cells wed by extensive regeneration of liver cells 59.A clinical study involves patients diagnosed with carcinoma and whose tumor stage is T4NIM1.The patients'survival rate 5 years from the time of diagnosis s of ther py.Which of the following clinical findings most likely to be characteristicof s group of patients?( A.Cachexia B.Cardiac murmur C.Icterus D.Loss of sensation E.Splenomegaly 60.A previously healthy 20 year old man develops heart failure over a period of several days.He is febrile and complains to his friends that he has chest pain, but he does not seek medical attention.He dies and an autopsy is performed. Examination of the heart shows that both ventricles are dilated bu otherwise the myocardium appears normal by gross visual inspection. An H&E-stained histologic section shows numerous inflammatory cells in the myocardium,more than 80%lymphocytes,which expand the interstitial spaces between individual myocytes and surround myoeytes.Most of the myoeytes are structurally intact house of a relative who is hosting a family reunion. She is hospitalized for surgery to replace a broken hip. She is then moved to a nursing home, but she is unable to ambulate until about a month later. She gets up to bathe with assistance and she experiences the sudden onset of severe dyspnea (shortness of breath) and goes into cardiac arrest, from which she cannot be resuscitated. Which of the following is most likely to be the immediate cause of death found at autopsy? ( ) A. Acute bronchopneumonia B. Acute renal failure C. Complications of alcohol abuse D. Congestive heart failure E. Pulmonary embolism 58. A 40-year-old man has a history of intravenous drug use. Physical examination shows needle tracks in his left antecubital fossa. He has mild scleral icterus (yellow eyeballs). Serologic studies for hepatitis HBsAg and antibodies to hepatitis HCV are positive. He develops hepatocellular carcinoma 15 years later at age 55. Which of the following best explains why this patient developed hepatocellular carcinoma? ( ) A. Integration of these viruses in the vicinity of protooncogenes B. The ability of these viruses to capture protooncogenes from the host DNA. C. These viruses cause immunosuppression. D. Viral genes inactivate RB and p53 expression E. Virus-induced injury to liver cells followed by extensive regeneration of liver cells 59. A clinical study involves patients diagnosed with carcinoma and whose tumor stage is T4N1M1. The patients’ survival rate 5 years from the time of diagnosis is less than 50%, regardless of therapy. Which of the following clinical findings is most likely to be characteristic of this group of patients? ( ) A. Cachexia B. Cardiac murmur C. Icterus D. Loss of sensation E. Splenomegaly 60. A previously healthy 20 year old man develops heart failure over a period of several days. He is febrile and complains to his friends that he has chest pain, but he does not seek medical attention. He dies and an autopsy is performed. Examination of the heart shows that both ventricles are dilated but otherwise the myocardium appears normal by gross visual inspection. An H&E-stained histologic section shows numerous inflammatory cells in the myocardium, more than 80% lymphocytes, which expand the interstitial spaces between individual myocytes and surround myocytes. Most of the myocytes are structurally intact