Fudan University Shanghai cancer Center Therapeutic Targets of Cancer EGFR Cyclin-dependent inhibitors kinase inhibitors Sustaining Aerobic glycolysis proliferative Immune activating inhibitors suppressors anti-CTLA4 mAb Deregulating Avoiding cellular mmune energetic Proapoptotic Resisting ase BH3 mimetics =← Inhibitors nstability promoting inflammation PARP Activating Selective anti- inhibitors inflammatory drugs Inhibitors of Inhibitors of VEGF signaling HGF/C-Met 复旦大学上海医学院肿瘤学糸 Hanahan. et al. Cell 2011: 144: 646Fudan University Shanghai Cancer Center 复旦大学上海医学院肿瘤学系 6 Therapeutic Targets of Cancer Hanahan D, et al. Cell. 2011;144:646