B Phagocytes with ingested microbes; Infected cell with microbial antigens in vesicles microbes in cytoplasm CD4+ effector CD8+1 CD8+ T cells T cells (TH1 cells) (CTLS)I (CTLS) Cytokine secretion Macrophage Inflammation Killing of activation→ infected cel killing of ingested microbes Abbas et al: Cellular and Molecular Immunology, Updated 6th Edition. Copyright 2009 by Saunders, an imprint of Elsevier, Inc. All rights reserved