Medical Genetics This means that mutations of mtDNA can be passed from mother to child. It also has implications if one does cloning of mammals with the use of somatic cells. the nuclear dna would be from the donor cell but the mtdna would be from the host cell. This is how dolly the sheep was clonedMedical Genetics This means that mutations of mtDNA can be passed from mother to child. It also has implications if one does cloning of mammals with the use of somatic cells. The nuclear DNA would be from the donor cell, but the mtDNA would be from the host cell. This is how Dolly the sheep was cloned