Thermophile and Biotechnology catalyzing biochemical reactions at gh of Enzymes from thermophiles are capable temperature, they are more stable DNA polymerase, Taq polymerase, has been isolated from thermophile- Thermus aquaticus, for PCR application DNA polymerase, pfu polymerase, isolated from hyperthermophile-Pyrocuccus furiosus, is more stable and useful for PCr application, it also less prone to errors Microbial process carried out at high t also eliminate or greatly reduce cooling costsThermophile and Biotechnology • Enzymes from thermophiles are capable of catalyzing biochemical reactions at high temperature, they are more stable; • DNA polymerase, Taq polymerase, has been isolated from thermophile-Thermus aquaticus, for PCR application; • DNA polymerase, pfu polymerase, isolated from hyperthermophile-Pyrocuccus furiosus, is more stable and useful for PCR application, it also less prone to errors; • Microbial process carried out at high T also eliminate or greatly reduce cooling costs