Treatment Tetracyclines, Rifampicin or ampicillin Symptomatic relief may occur within a few days after treatment however because of their intracellular location treatment must be prolonged Combined treatment with a tetracycline and either streptomycin for 2-3 weeks or rifampin for 6 weeks is recommendedTreatment • Tetracyclines, Rifampicin or ampicillin • Symptomatic relief may occur within a few days after treatment. However, because of their intracellular location, treatment must be prolonged. • Combined treatment with a tetracycline and either streptomycin for 2-3 weeks or rifampin for 6 weeks is recommended