Gangrene 。Ischemia Loss of blood supply to tissue ·Necrosis 。Death of tissue 。Gangrene ·Death of soft tissue ·Gas gangrene Clostridium perfringens,gram-positive,endospore- forming anaerobic rod,grows in necrotic tissue Treatment includes surgical removal of necrotic tissue and/or hyperbaric chamber• Ischemia • Loss of blood supply to tissue • Necrosis • Death of tissue • Gangrene • Death of soft tissue • Gas gangrene • Clostridium perfringens, gram-positive, endospore￾forming anaerobic rod, grows in necrotic tissue • Treatment includes surgical removal of necrotic tissue and/or hyperbaric chamber Gangrene