Multiple regression Least squares criterion min e2=min(-. The formulae for the regression coefficients bo by b2 b, involve the use of matrix algebra. We will rely on computer software packages to perform the calculations b i represents an estimate of the change in Y corresponding to a one-unit change in X; when all other independent variables are held constant Slide 6Slide 6 Multiple Regression • Least Squares Criterion • The formulae for the regression coefficients b0 , b1 , b2 , . . . bp involve the use of matrix algebra. We will rely on computer software packages to perform the calculations. • bi represents an estimate of the change in Y corresponding to a one-unit change in Xi when all other independent variables are held constant.   = = = − n i i i n i ei Y Y 1 2 1 2 ) ˆ min min (