months of life and some of the diagnosis criteria, are as follows: the sweat test, may fail in certain patients which makes their identification difficult and may be taken for granted in the childhood There is also the presence of patient s cariers of Cystic Fibrosis Transmembrane conductance gene mutation, who present with a higher proneness to the chronic sinusitis, recurrent pancreatitis or vas deferens obstruction without other features of the disease, which may conf use the diagnosis. However, it cannot fully determine how severe patients Cystic Fibrosis will be in the future Treatment The objective of the treatment is to reduce the patient s symptoms through the re-establishing of nasosinusal ventilation and draining to control infections, eliminate the pulmonary infection reservoir and improve the patients nutritional state. Despite the use of medications or even surgery, the patients with Cystic Fibrosis are not cured. Basically treating patients with Cystic Fibrosis means to improve the quality of life, not suffering from recurring infections. Hence, various treatments and therapy are done cautiously to the people suffering with Cystic Fibrosis, such are the nasal treatment consists of washing with saline solution, intranasal corticosteroids antimicrobial therapy and Functional Endoscopic Sinus Surgery(FESS). Another treatment is the saline olution is aimed at liquidifying the secretion and providing nasal hygiene. It may be used in isotonic or hypertonic imigations with the advantage of decongesting the nose The antibiotics are the most important medications in the Cystic Fibrosis treatment. They must cover quinolone antibiotics, despite these are not released for children by the FDA. other antibiotics used ap and Pseudomonas, Staphylococcus, as well as the anaerobe germs. The mostly used are the aminosidine piperacillin, ceftazidime and imipenem. Moreover, there are a lot of risks on undertaking the surgery since the patients situation isn't stable because of their advanced pulmonary disorder, extensive sinusal disease, anatomic changes caused by prior surgeries, coagulopathy for vitamin K deficiency, pancreatic and hepatic diseases, as well as nutritional deficiency. In spite of rigorous treatment, the recurrence is a rule and the average of free time from symptoms ranges from 1 to 4 years Final Consideration Despite otorhinolaryngological manifestations arent the main cause of death in the Cystic Fibrosis patients however, it does bring a significant morbidity. With the extensive research going on for decades, the life expectancy of Cystic Fibrosis patients has increased dramatically especially when the antibiotic therapy and improvement of surgical techniques was administered to the patients. As per today there is no exact cure for Cystic Fibrosismonths of life and some of the diagnosis criteria, are as follows: the sweat test, may fail in certain patients, which makes their identification difficult and may be taken for granted in the childhood. There is also the presence of patient’s carriers of Cystic Fibrosis Transmembrane conductance gene mutation, who present with a higher proneness to the chronic sinusitis, recurrent pancreatitis or vas deferens obstruction without other features of the disease, which may confuse the diagnosis. However, it cannot fully determine how severe patients Cystic Fibrosis will be in the future. Treatment The objective of the treatment is to reduce the patient's symptoms through the re-establishing of nasosinusal ventilation and draining, to control infections, eliminate the pulmonary infection reservoir and improve the patient's nutritional state. Despite the use of medications or even surgery, the patients with Cystic Fibrosis are not cured. Basically treating patients with Cystic Fibrosis means to improve the quality of life, not suffering from recurring infections. Hence, various treatments and therapy are done cautiously to the people suffering with Cystic Fibrosis, such are the nasal treatment consists of washing with saline solution, intranasal corticosteroids, antimicrobial therapy and Functional Endoscopic Sinus Surgery (FESS). Another treatment is the saline solution is aimed at liquidifying the secretion and providing nasal hygiene. It may be used in isotonic or hypertonic irrigations with the advantage of decongesting the nose. The antibiotics are the most important medications in the Cystic Fibrosis treatment. They must cover Pseudomonas, Staphylococcus, as well as the anaerobe germs. The mostly used are the aminosidine and quinolone antibiotics, despite these are not released for children by the FDA. Other antibiotics used are piperacillin, ceftazidime and imipenem. Moreover, there are a lot of risks on undertaking the surgery since the patients situation isn’t stable because of their advanced pulmonary disorder, extensive sinusal disease, anatomic changes caused by prior surgeries, coagulopathy for vitamin K deficiency, pancreatic and hepatic diseases, as well as nutritional deficiency. In spite of rigorous treatment, the recurrence is a rule and the average of free time from symptoms ranges from 1 to 4 years. Final Considerations Despite otorhinolaryngological manifestations aren’t the main cause of death in the Cystic Fibrosis patients, however, it does bring a significant morbidity. With the extensive research going on for decades, the life expectancy of Cystic Fibrosis patients has increased dramatically especially when the antibiotic therapy and improvement of surgical techniques was administered to the patients. As per today, there is no exact cure for Cystic Fibrosis