What are Watson-Crick base pairs?Why are they important? What characteristic of DNA results in the requirement that some DNA synthesis be discontinuous? What is the proofreading mechanism in DNA replication? What is the function of the slide clamp?What is the consequence without the slide clamp? Describe the problem that occurs during DNA replication at the ends of chromosomes.How are telomeres related to this problem? What are the three excision-repair systems found in eukaryotes,and which one is responsible for correcting thymine-thymine dimers that form as a result of UV light damage to DNA? Briefly describe the similarities and differences of the two processes that can repair double-strand breaks. 七、学习资源、课外自主学习参考 (可以列出供学生进一步学习、拓展本章节内容的网站、著作、期刊的名称及内容等) Molecular Biology of the Cell,Alberts等编著，第六版，2014年出版，Garland Science Molecular Biology::Principles and Practice,Michael Cox等编著，第二版，2015 年出版，W.H.Freeman and Company Molecular Biology,,Robert Weaver,第五版，20l2年出版，McGraw-Hill• What are Watson-Crick base pairs? Why are they important? • What characteristic of DNA results in the requirement that some DNA synthesis be discontinuous? • What is the proofreading mechanism in DNA replication? • What is the function of the slide clamp? What is the consequence without the slide clamp? • Describe the problem that occurs during DNA replication at the ends of chromosomes. How are telomeres related to this problem? • What are the three excision-repair systems found in eukaryotes, and which one is responsible for correcting thymine-thymine dimers that form as a result of UV light damage to DNA? • Briefly describe the similarities and differences of the two processes that can repair double-strand breaks. 七、学习资源、课外自主学习参考 (可以列出供学生进一步学习、拓展本章节内容的网站、著作、期刊的名称及内容等)  Molecular Biology of the Cell，Alberts 等编著，第六版，2014 年出版，Garland Science  Molecular Biology: Principles and Practice, Michael Cox 等编著, 第二版，2015 年出版，W. H. Freeman and Company  Molecular Biology, Robert Weaver, 第五版，2012 年出版，McGraw-Hill