Neurologic manifestation Central Daytime drowsiness, a tendency to sleep, coma Decreased attentiveness Seizures Disorientation and confusion Peripheral Restless leg syndrome Sensorimotor peripheral neuropathy Increased muscle fatigability and muscle cramps12 Neurologic Manifestation • Central – Daytime drowsiness,a tendency to sleep,coma – Decreased attentiveness – Seizures – Disorientation and confusion • Peripheral – Restless leg syndrome – Sensorimotor peripheral neuropathy – Increased muscle fatigability and muscle cramps