CH3CH2CH2 Biological Oxidation斷0H H HH Catalyzed by ADh, alcohol dehydrogenase Oxidizing agent is NAD*t, nicotinamide adenine dinucleotide Ethanol oxidizes to acetaldehyde then acetic acid. a normal metabolite Methanol oxidizes to formaldehyde then formic acid. more toxic than methanol Ethylene glycol oxidizes to oxalic acid, toxic Treatment for poisoning is excess ethanol Chapter 11 10CH3CH2CH2 C H H Br O H H Chapter 11 10 Biological Oxidation • Catalyzed by ADH, alcohol dehydrogenase. • Oxidizing agent is NAD+ , nicotinamide adenine dinucleotide. • Ethanol oxidizes to acetaldehyde, then acetic acid, a normal metabolite. • Methanol oxidizes to formaldehyde, then formic acid, more toxic than methanol. • Ethylene glycol oxidizes to oxalic acid, toxic. • Treatment for poisoning is excess ethanol. =>