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gestational age(however defined by authors) mean weight; mean placental weight; mean head circumference: admission to neonatal intensive cares mean skin fold thickness need for inotropic support; abnormal lung function(however defined by authors) mean duration of inotropic support( days) mean blood pressure; need for mechanical ventilation/continuous positive airways glucose intolerance(however defined by authors) HPA axis function(however defined by authors) uration of mechanical ventilation dyslipidaemia(however defined by authors air leak syndrome; mean age at puberty; duration of oxygen supplementation( days) bone density(however defined by authors); . surfactant use. educational achievement(completion of high school, or how systemic infection in first 48 hours of life; ever defined by authors ); visual proven infection while in the neonatal intensive care unit; ment(however defined by authors hypothalamo-pituitary-adrenal(HPA)axis function(however intellectual impairment(defined as intelligence quotient less n-2 standard deviation below pop For the child: For health services: head circumference: 四bp包时 h of neonatal hosp mean skin fold thickness cost of maternal care(in 10s of 1000s of S abnormal lung function(however defined by authors) cost of neonatal care(in 10s of 1000s of S) · mean blood pressure; Although all outcomes were sought from included trials, only tri- als with relevant data appear in the analysis tables Outcomes were glucose intolerance(however defined by authors) included in the analysis if reasonable measures were taken to min- HPA axis function(however defined by authors) imise observer bias and data were available for analysis according to origin dyslipidaemia(however defined by authors) visual impairment(however defined by authors); The following subgroups were analysed hearing impairment(however defined by authors) developmental delay (defined as developmental quotient less gestational age at delivery(< 28 weeks, <30 weeks, 32 weeks, than-2 standard deviation below population mean 34 weeks, 36 weeks, at least 34 weeks, at least 36 weeks) intellectual impairment (defined as intelligence quotient less an-2 standard deviation below population mean) entry to delivery interval (< 24 hours, 48 hours, one to seven seven (however defined by authors); prelabour rupture of membranes(at trial entry. >24 hours be- behavioural/learning difficulties(however defined by authors). fore delivery, >48 hours before delivery) For the child as adult: pregnancy induced hypertension syndromes: Antenatal corticosteroids for accelerating fetal lung maturation fe nen at risk of preterm birth( Review) Copyright @2006 The Cochrane Collaboration. Published by John wiley& Sons, Ltd• small-for-gestational age (however defined by authors); • mean placental weight; • neonatal blood pressure; • admission to neonatal intensive care; • need for inotropic support; • mean duration of inotropic support (days); • need for mechanical ventilation/continuous positive airways pressure; • mean duration of mechanical ventilation/continuous positive airways pressure (days); • air leak syndrome; • duration of oxygen supplementation (days); • surfactant use; • systemic infection in first 48 hours of life; • proven infection while in the neonatal intensive care unit; • necrotising enterocolitis; • hypothalamo-pituitary-adrenal (HPA) axis function (however defined by authors). For the child: • mean weight; • mean head circumference; • mean length; • mean skin fold thickness; • abnormal lung function (however defined by authors); • mean blood pressure; • glucose intolerance (however defined by authors); • HPA axis function (however defined by authors); • dyslipidaemia (however defined by authors); • visual impairment (however defined by authors); • hearing impairment (however defined by authors); • developmental delay (defined as developmental quotient less than -2 standard deviation below population mean); • intellectual impairment (defined as intelligence quotient less than -2 standard deviation below population mean); • cerebral palsy (however defined by authors); • behavioural/learning difficulties (however defined by authors). For the child as adult: • mean weight; • mean head circumference; • mean length; • mean skin fold thickness; • abnormal lung function (however defined by authors); • mean blood pressure; • glucose intolerance (however defined by authors); • HPA axis function (however defined by authors); • dyslipidaemia (however defined by authors); • mean age at puberty; • bone density (however defined by authors); • educational achievement (completion of high school, or how￾ever defined by authors); • visual impairment (however defined by authors); • hearing impairment (however defined by authors); • intellectual impairment (defined as intelligence quotient less than -2 standard deviation below population mean). For health services: • mean length of antenatal hospitalisation for women (days); • mean length of postnatal hospitalisation for women (days); • mean length of neonatal hospitalisation (days); • cost of maternal care (in 10s of 1000s of $); • cost of neonatal care (in 10s of 1000s of $). Although all outcomes were sought from included trials, only tri￾als with relevant dataappear in theanalysis tables. Outcomes were included in the analysis if reasonable measures were taken to min￾imise observer bias and data were available for analysis according to original allocation. Subgroup analysis The following subgroups were analysed: • singleton versus multiple pregnancy; • gestational age at delivery (< 28 weeks, < 30 weeks, < 32 weeks, < 34 weeks, < 36 weeks, at least 34 weeks, at least 36 weeks); • entry to delivery interval (< 24 hours, < 48 hours, one to seven days, > seven days); • prelabour rupture of membranes (at trial entry, > 24 hours be￾fore delivery, > 48 hours before delivery); • pregnancy induced hypertension syndromes; Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review) 5 Copyright © 2006 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd 第 99 页
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