Making a Gene Product Master plate with colonies of bacteria containing cloned segments of foreign genes. Nitrocellulose Make replica of master plate on filter nitrocellulose filter. Treat filter with detergent(SDS)to lyse bacteria. Strands of bacterial DNA Treat filter with sodium hydroxide(NaOH) to separate DNA into single strands. Radioactively labeled probes Add radioactively labeled probes. Figure 9.12.1Making a Gene Product Figure 9.12.1