B Cell Antigen Recognition Cell surface immunoglobulin receptor or B-cell receptor (IgM and IgD) Antigen contact initiates B-cell activation,clonal expansion,maturation to plasma cell Antigen receptor is identical to immunoglobulin that will ultimately be produced B Cell Antigen Recognition ◼ Cell surface immunoglobulin receptor or B-cell receptor (IgM and IgD) ◼ Antigen contact initiates B-cell activation, clonal expansion, maturation to plasma cell ◼ Antigen receptor is identical to immunoglobulin that will ultimately be produced