Chapter 7. Scale-Up 8.1 Similitude For the optimum design of a production-scale fermentation system(prototype), we must translate the data on a small scale(model)to the large scale. The fundamental requirement for scale-up is that the model and prototype should be similar to each other Two kinds of conditions must be satisfied to ensure similarity between model and prototype They are: (1)Geometric similarity of the physical boundariesChapter 7. Scale-Up 8.1 Similitude For the optimum design of a production-scale fermentation system (prototype), we must translate the data on a small scale (model) to the large scale. The fundamental requirement for scale-up is that the model and prototype should be similar to each other. Two kinds of conditions must be satisfied to ensure similarity between model and prototype. They are: (1) Geometric similarity of the physical boundaries: