Medical Genetics 1 Biochemical Genetic abnormalities of mitochondrial function (1) Mitochondrial substrate transport (2)Substrate utilization (3)Citric acid (tcA) cycle (4)Oxidation-Phosphorylation coupling ()Respiratory chain (6) Lipid membrane defect ()Nuclear gene defectsMedical Genetics 1. Biochemical & Genetic abnormalities of mitochondrial function (1) Mitochondrial substrate transport (2) Substrate utilization (3) Citric acid (TCA) cycle (4) Oxidation-Phosphorylation coupling (5) Respiratory chain (6) Lipid membrane defect: (7) Nuclear gene defects