Role of Regeneration in Tissue Repair In labile tissues,injured cells are rapidly replaced by proliferation of residual cells and differentiation of tissue stem cells provided the underlying basement membrane is intact. Tissue regeneration can occur in parenchymal organs with stable cell populations,but with the exception of the liver o The regenerative response of the liver that occurs after surgical removal of hepatic tissue is remarkable and unique among all organsRole of Regeneration in Tissue Repair  In labile tissues, injured cells are rapidly replaced by proliferation of residual cells and differentiation of tissue stem cells provided the underlying basement membrane is intact.  Tissue regeneration can occur in parenchymal organs with stable cell populations, but with the exception of the liver  The regenerative response of the liver that occurs after surgical removal of hepatic tissue is remarkable and unique among all organs