Thyroid hormone--intracorporal process Tab 1 Summary of thyroid hormone kinetics kinetics daily production(ug) 70≈90 15~30 fractional turnover per day ( % 10 60 metabolic clearance per day l/d 24 amount bound (%) 99.96 996 volume of distribution (l) 10 40 serum level (total)( ug/dL) 4.5~11 60~180 serum level(free)(ng/dL) 0.7~186 0.2~0.52 half-life(biologic)(d) 7 biological potency orarabaarption(% 80kinetics T４ T3 daily production (µg) 70～90 15～30 fractional turnover per day (%) 10 60 metabolic clearance per day (L/d) 1.1 24 amount bound (％) 99.96 99.6 volume of distribution (Ｌ) 10 40 serum level(total) ( µg/dL) 4.5～11 60～180 serum level(free) (ng/dL) 0.7～1.86 0.2～0.52 half-life(biologic) (d) 7 1 biological potency 1 4 oral absorption (%) 80 95 Tab 1 Summary of thyroid hormone kinetics