Clearing the Air Indoor Air Exposures Asthma EXacerbation Biological Agents Chemical Agents Sufficient evidence of causal Sufficient evidence of causal relationship relationship Environmental tobacco smoke Cat (among pre-school aged children) Cockroach Sufficient evidence of association House dust mite NO2, NOx(high levels Sufficient evidence of an association Limited or suggestive evidence of association Dog Environmental Tobacco smoke Fungus/Molds among school-aged older children, and adults) · Rhinovirus Formaldehyde Limited or suggestive evidence of Fragrances association Domestic birds Chlamydia and Mycoplasma pneumonia RSVClearing the Air: Indoor Air Exposures & Asthma Exacerbation Biological Agents – Sufficient evidence of causal relationship • Cat • Cockroach • House dust mite – Sufficient evidence of an association • Dog • Fungus/Molds • Rhinovirus – Limited or suggestive evidence of association • Domestic birds • Chlamydia and Mycoplasma pneumonia • RSV Chemical Agents • Sufficient evidence of causal relationship – Environmental tobacco smoke (among pre-school aged children) • Sufficient evidence of association – NO2 , NOX (high levels) • Limited or suggestive evidence of association – Environmental Tobacco Smoke (among school-aged, older children, and adults) – Formaldehyde – Fragrances