Pathologic jaundice It appears in the 1st 24-36hr of life Serum bilirubin is rising at a rate faster than 5 mg/d/24hr. Serum bilirubin is 2 12 mg/dl in full-term or 10 14 mg/dl in preterm infants Jaundice persists after 10-14 days of life Direct-reacting bilirubin is 22 mg/dl at any time Among other factors suggesting a nonphysiologic cause of jaundice.Pathologic jaundice ◼ It appears in the 1st 24-36hr of life ◼ Serum bilirubin is rising at a rate faster than 5 mg/dl/24hr. ◼ Serum bilirubin is ≥ 12 mg/dl in full-term or 10- 14 mg/dl in preterm infants. ◼ Jaundice persists after 10-14 days of life. ◼ Direct-reacting bilirubin is ≥ 2 mg/dl at any time. ◼ Among other factors suggesting a nonphysiologic cause of jaundice