2. Exp lain the characteristic of mitochondrial disease Threshold effect Mitotic segregation Maternal inheritance 3. Describe the symptoms and the genotype of Cystic fibrosis An autosomal recessive disorder caused by mutations in the cF transmembrane regulator gene (CFTR) located at 7q31.2. Symptoms include: abnormal chloride ion transport in exocrine tissues leading to the accumulation of mucus in hangs, sinuses, intestines, pancreas and male reproductive tract. 4. analyze the pedigree, what inheritance model do you think? Why? XD 5. analyze the pedigree, what inheritance model do you think? why? Ylinked Section C: Consulting questions(51%) 1. Key points: mothers age and down syndrome 2. schizophrenia is poly gene disorder and the risk is related with relative class. CPEO is mitochondrial disease and it is maternal inheritance 3. Hemop hilia B is XR model, and draw the pedigree of the family2. Explain the characteristic of mitochondrial disease Threshold effect Mitotic segregation Maternal Inheritance 3. Describe the symptoms and the genotype of Cystic fibrosis An autosomal recessive disorder caused by mutations in the CF transmembrane regulator gene (CFTR) located at 7q31.2.Symptoms include: abnormal chloride ion transport in exocrine tissues leading to the accumulation of mucus in lungs, sinuses, intestines, pancreas and male reproductive tract. 4. analyze the pedigree，what inheritance model do you think? Why? XD 5. analyze the pedigree，what inheritance model do you think? Why? Y linked Section C: Consulting & questions(51%) 1. Key points: mothers age and Down syndrome. 2. schizophrenia is polygene disorder and the risk is related with relative class. CPEO is mitochondrial disease and it is maternal Inheritance. 3. Hemophilia B is XR model, and draw the pedigree of the family