Contractions of Intestinal Smooth Museles Occur automatically in Slow waves response to endogenous 28 pacemaker activity Rhythm of contractions is mV paced by graded depolarizations called slow waves 5 sec Slow waves produced by interstitial cells of Cajal Slow waves spread from I smooth muscle cell to another through nexuses 33 Contractions of Intestinal Smooth Muscles • Occur automatically in response to endogenous pacemaker activity. • Rhythm of contractions is paced by graded depolarizations called slow waves. •Slow waves produced by interstitial cells of Cajal. •Slow waves spread from 1 smooth muscle cell to another through nexuses