Comparisons of simulations with in vivo measurements in a sheep 上 游充通大￥ 110 100 50 Aortic Blood Pressure Blood FLow throuch Pumo 100 90 40 40 ⑦ 60 Pump Flowm/s) Pump Flowml/s) 20 10 30- 10 36.0 36.5 37.0 37.5 38.0 38.5 39.0 7.07.2747.67.880828.4868.89.092949.69.810.0 Time(s) The CVS-artificial-heart model might contribute as a mathematical tool for designing patient-specific artificial heart. Without Pump 30- Pump Mean:72.59 ml/s -Wth Pump With Pump -Without Pump 90 130 20 150 80 ean:77.38 ml/s 70 50 0 g0- 50 359 372 50 39 372 369 32 Time(s) Time(s) Time(s) Left ventricular volume Blood flow through the ascending aorta Ascending aortic pressureComparisons of simulations with in vivo measurements in a sheep 7.0 7.2 7.4 7.6 7.8 8.0 8.2 8.4 8.6 8.8 9.0 9.2 9.4 9.6 9.8 10.0 30 40 50 60 70 80 90 100 110 Aortic Blood Pressure Blood FLow through Pump Time(s) Aortic Pressure(mmHg) 10 20 30 40 50 Pump Flow(ml/s) 36.0 36.5 37.0 37.5 38.0 38.5 39.0 70 80 90 100 Time(s) Aortic Pressure(mmHg) 10 20 30 40 50 Pump Flow(ml/s) Measurements Predictions 36.9 37.2 90 100 110 120 130 140 150 Left Ventricular Volume(ml) Time(s) Without Pump With Pump 36.9 37.2 -50 0 50 100 150 200 250 300 Mean:77.38 ml/s Mean:72.59 ml/s Blood Flow towards Aorta(ml/s) Time(s) With Pump Without Pump 36.9 37.2 50 60 70 80 90 100 Aortic Pressure(mmHg) Time(s) With Pump Without Pump Left ventricular volume Blood flow through the ascending aorta Ascending aortic pressure The CVS-artificial-heart model might contribute as a mathematical tool for designing patient-specific artificial heart