河北医科大学药学院2018 Taxol Chemical Shift (ppm) 18 天然药物化学教研室史清文教授 2 河北医科大学药学院2018 天然药物化学教研室史清文教授 2 8 7 6 5 4 3 2 1 Chemical Shift (ppm) 1 0 P h N H 1 3 2 0 a ,2 0 b 5 3 7 2 2 ' 3 ' HO OAc O OBz H O O OH O NH OH O AcO 2 4 7 10 13 15 1' 2' 18 19 20 16 3' 5 6 3 14 1 12 11 17 8 Taxol 183 7 6 5 4 3 2 1 Chemical Shift (ppm) Chloroform-d 6.5 6.4 6.3 6.2 Chemical Shift (ppm) 5.20 5.15 5.10 Chemical Shift (ppm) 4.00 3.95 3.90 Chemical Shift (ppm) H3C HO CH3 CH3 OH H H CH3 CH3 H3C HO 184