Contents PrefaceⅨ Part 1 Early Recognition and Diagnosis 1 Chapter 1 Early Detection of Autism Spectrum Disorders 3 Jariya Chuthapisith and Nichara Ruangdaraganon Part 2 Nosology and Diagnostic Criteria: What Makes Sense and Can Genetics Help? 15 Chapter 2 Pervasive Developmental Disorder-not Otherwise Specified: Specifying and Differentiating 17 Koray Karabekiroglu Chapter 3 Autism and Genetic Syndromes 31 Willem Verhoeven, Jos Egger and lse Feenstra Part 3 Genetics and Pathophysiology of Autism Spectrum Disorders 49 Chapter 4 The Genetics of Autism Spectrum Disorders 51 John J.M. Connolly and Hakon Hakonarson Chapter 5 Genetic Heterogeneity of Autism Spectrum Disorders 65 Catherine Croft swanwick Eric C. Larsen and Sharmila banerjee-Basu Chapter 6 The Genetic Basis of Phenotypic Diversity: Autism as an Extreme Tail of a Complex Dimensional Trait 83 linji Ijichi, Naomi jichi, Yukina Jic Hisami Sameshima and Hirofumi morioka Chapter 7 A New Genetic Mechanism for Autism 103 Julie Gauthier and Guy A. RouleauContents Preface IX Part 1 Early Recognition and Diagnosis 1 Chapter 1 Early Detection of Autism Spectrum Disorders 3 Jariya Chuthapisith and Nichara Ruangdaraganon Part 2 Nosology and Diagnostic Criteria: What Makes Sense and Can Genetics Help? 15 Chapter 2 Pervasive Developmental Disorder- not Otherwise Specified: Specifying and Differentiating 17 Koray Karabekiroglu Chapter 3 Autism and Genetic Syndromes 31 Willem Verhoeven, Jos Egger and Ilse Feenstra Part 3 Genetics and Pathophysiology of Autism Spectrum Disorders 49 Chapter 4 The Genetics of Autism Spectrum Disorders 51 John J.M. Connolly and Hakon Hakonarson Chapter 5 Genetic Heterogeneity of Autism Spectrum Disorders 65 Catherine Croft Swanwick, Eric C. Larsen and Sharmila Banerjee-Basu Chapter 6 The Genetic Basis of Phenotypic Diversity: Autism as an Extreme Tail of a Complex Dimensional Trait 83 Shinji Ijichi, Naomi Ijichi, Yukina Ijichi, Hisami Sameshima and Hirofumi Morioka Chapter 7 A New Genetic Mechanism for Autism 103 Julie Gauthier and Guy A. Rouleau