Passage 3 Directions: There are 10 blanks in the following passage. For each blank there are four choices marked A.B. C. and D. You should choose the one that best fits into the passage Patients and tumors are_ 1, The conceptual design is great. Identifying the genetic variants underlying phenotype can lead to personalized medicine. 2 the best medical intervention to the right individual or patient can dramatically improve health The use of personalized medicine to improve both the prevention and cure of disease is potentially achievable through: predicting both the disease 3 among healthy individuals in the general population and the therapeutic response among patients. Genomic information from individuals or patients can substantially biomarker-based guided personalized prevention and treatment. The first strategy to use personalized medicine, in the prevention setting,- 5 identifying high-risk individuals that may develop major common diseases, such as cardiovascular disorder, diabetes and cancer, and then 6 the most appropriate preventive intervention to protect them from these diseases. This strategy can substantially reduce disease_7 and it is particularly important for 8 disorders, such as cancer. In the second strategy, in the treatment 9, efforts by academia and industry have been focused on how to improve diagnostics and prognosis of diseases hrough the development of predictors of drug response and adverse 1 improve the safety and efficacy of drugs 1. A. same B. special C D. different 2. A. Obtaining B. Tailoring C. Treating B. sIgn symptom 4. A. attend B. attribute C. distribute D. contribute 5. A. involves B. involvi ng C. involved D. is involved 6. A. selec B. selecting D. have selected 7. A. severity B. h C. accident D 8. A. being hard B. hard treated C. hardly treated D. hard-to-treat 9.A. ward B. clinic C. setting D. option 10. A. efficiency B. effect C. efficacy proficiencyPassage 3 Directions: There are 10 blanks in the following passage. For each blank there are four choices marked A, B, C, and D. You should choose the ONE that best fits into the passage. Patients and tumors are 1 . The conceptual design is great. Identifying the genetic variants underlying phenotype can lead to personalized medicine. 2 the best medical intervention to the right individual or patient can dramatically improve health. The use of personalized medicine to improve both the prevention and cure of disease is potentially achievable through: predicting both the disease 3 among healthy individuals in the general population and the therapeutic response among patients. Genomic information from individuals or patients can substantially 4 to biomarker-based guided personalized prevention and treatment. The first strategy to use personalized medicine, in the prevention setting, 5 identifying high-risk individuals that may develop major common diseases, such as cardiovascular disorder, diabetes and cancer, and then 6 the most appropriate preventive intervention to protect them from these diseases. This strategy can substantially reduce disease 7 and it is particularly important for 8 disorders, such as cancer. In the second strategy, in the treatment 9 , efforts by academia and industry have been focused on how to improve diagnostics and prognosis of diseases and how, through the development of predictors of drug response and adverse 10 , to improve the safety and efficacy of drugs. 1. A. same B. special C. unique D. different 2. A. Obtaining B. Tailoring C. Treating D. Targeting 3. A. risk B. sign C. symptom D. incidence 4. A. attend B. attribute C. distribute D. contribute 5. A. involves B. involving C. involved D. is involved 6. A. selects B. selecting C. selected D. have selected 7. A. severity B. happening C. accident D. incidence 8. A. being hard treat B. hard treated C. hardly treated D. hard-to-treat 9. A. ward B. clinic C. setting D. option 10. A. efficiency B. effect C. efficacy D. proficiency