Systemic Inflammatory Response Syndrome -SIRS Clinial syndrome manefested with strong inflmmation over-responsiveness of inflamatory mediators all over the body(cytokines Cascade) · pathogenic factors: infection: bacteria. virus non-infection: in juries, burns outcome organ and tissue injuriesClinial syndrome manefested with strong inflmmation • over-responsiveness of inflmmatory mediators all over the body(cytokines Cascade） • pathogenic factors： infection:bacteria,virus,… non-infection:injuries,burns,… • outcome：organ and tissue injuries Systemic Inflammatory Response Syndrome -SIRS