DNA Sequence AlignmentⅨ The single most useful thing there is to know about mismatch penalties m=in(4(1-)3)/n<4r) Examples 0.750.95099 ra desired fraction of identities in blast hitsDNA Sequence Alignment IX The single most useful thing there is to know about mismatch penalties: m = ln(4(1-r)/3)/ln(4r) Examples: r 0.75 0.95 0.99 m -1 -2 -3 r = desired fraction of identities in BLAST hits