TABLE 9.1 Some Pharmaceutical Products of Genetic Engineering(continued) Product Comments Influenza vaccine Trial vaccine made from E.coli or S.cerevisiae carrying virus genes. Interleukins Regulate the immune system;possible treatment for cancer;produced by E.coli. Monoclonal antibodies Possible therapy for cancer and transplant rejection;used in diagnostic tests;produced by mammalian cell culture(from fusion of cancer cell and antibody-producing cell). Orthoclone Monoclonal antibody used in transplant patients to help suppress the immune system, reducing the chance of tissue rejection;produced by mouse cells. Prourokinase Anticoagulant;therapy for heart attacks;produced by E.coli and yeast. Pulmozyme(rhDNase) Enzyme used to break down mucous secretions in cystic fibrosis patients;produced by mammalian cell culture. Relaxin Used to ease childbirth;produced by E.coli. Superoxide dismutase (SOD) Minimizes damage caused by oxygen free radicals when blood is resupplied to oxygen-deprived tissues;produced by S.cerevisiae and Pichia pastoris (yeast). Taxol Plant product used for treatment for ovarian cancer;produced in E.coli. Tissue plasminogen activator Dissolves the fibrin of blood clots;therapy for heart atacks;produced by mammalian (Activase) cell culture. Tumor necrosis factor (TNF) Causes disintegration of tumor cells;produced by E.coli. Table 9.1.2 Table 9.1.2