Differential diagnoses Clues. Fever, chill, high WBC and N% Cough, short of breath on exertion poor oxygenation Multiple cavitary and pre-cavitary lesions Intravenous drug abuse in the past Work in basements that were damp and moldy. Azithromycin treatment failure Differential diagnoses: Lung infection Tuberculosis, fungal Blood stream infection: endocarditis Non-infection disease: Wegener granulomatosisDifferential diagnoses ? • Clues: • Fever, chill, high WBC and N% • Cough, short of breath on exertion, poor oxygenation • Multiple cavitary and pre-cavitary lesions • Intravenous drug abuse in the past • Work in basements that were damp and moldy. • Azithromycin treatment failure • Differential diagnoses： • Lung infection: Tuberculosis, fungal • Blood stream infection: endocarditis • Non-infection disease: Wegener granulomatosis