河北医科大学药学院 植物抗毒素Phytoalexin- 防御来自地下的进 Stevioside 物保扩素K.Mr1952名 Natural Sweeter from Plants Poison Ivy and Urushiol 只有箭是甜的吗？ Irmshiol-induced cont山et derma Can We Eat Mango Skin? Contact Dermatitis接触性皮肤炎 Perioral dermatitis caused by mang otosin 1947 天然药物化学教研室史清文教授河北医科大学药学院 天然药物化学教研室史清文教授 4 植物抗毒素 Phytoalexin— 防御来自地下的进攻 Capsidiol 植物保护素 K．Mller 1952年命名 O OH HO O O H3CO O O OH HO HO OH OH Pisatin Luteolindin Stevioside H COO--Glu O-Glu--Glu(2 1) H 甜菊Stevia rebaudianum Beaoni叶中含有以对映-贝壳杉烷(ent￾kaurane)骨架为母核，与不同糖组成的甜味苷，即甜菊苷(stevioside)及甜 菊苷A、D、E (rebaudiosides A，D，E)等多种甜味苷。总甜菊苷含量约 6%，其甜度约为蔗糖的300倍，其中又以甜菊苷A甜味最强。 O OH H Hernandulcin O O O HO O OH HO O OH H3C HO HO Baiyunoside Polypodoside A O O H H H H O HO O OH HO OH HO HO Me O O O OH OH OH Me Natural Sweeter from Plants Phyllodulcin O O H OCH3 OH OH 400 600 1500 500 只有糖是甜的吗？ Poison Ivy and Urushiol poison ivy 毒葛 Urushiol-induced contact dermatitis HO OH Urushiol Can We Eat Mango Skin? Is It Okay To Eat Mango Skin? Allergic reaction to mango was first described in 1939 Mangifera indica Perioral dermatitis caused by mango Contact Dermatitis 接触性皮肤炎 Cicutoxin Oenanthotoxin 1947 carotatoxin