磺酸脂的水解 R +(CF3SO2)O C5H5N SO2 CF3 (FSOR) OH R R2 OH +CH3SO2CI-C5HsN SO2 CH3(MSOR) R R +HC〈xso2CI SO2PhCH3 (TSOR) oLi R“O 活性:FS0>Ts0>M0>>Br>Cl 叔醇磺酸酯难以合成、也不稳定、易生成烃 TsCI Et3N OH OTs磺酸脂的水解 活性：FsO > TsO > MsO > I > Br > Cl 叔醇磺酸酯难以合成、也不稳定、易生成烯烃. R2 OH R1 (CF3SO2 )O C5H5N R2 O R1 SO2CF3 R2 OH R1 C5H5N R2 O R1 CH3SO2Cl SO2CH3 (MsOR) R2 OLi R1 R2 O R1 H SO2PhCH3 (TsOR) 3C SO2Cl + (FsOR) + + OH TsCl Et3N R OTs OH