Antigen presentation Antigen recognition and T cell activation by b cells Parafollicular Lymphoid Microbe Microbe cortex(T cell follicle Naive CD4 zone) (B cell B Lymph: T cell zone) B cell node activation APC T cell proliferation and differentiation Migration Effector CD4 T: B cel H/+ Mig gration T cells interactions OElsevierAbbas&LichtmanBasicImmunologyUpdated2e-www.studentconsult.com The interactions of Th cells and b cells in lymphoid tissues.The interactions of Th cells and B cells in lymphoid tissues